{"id":78,"date":"2022-11-09T06:10:58","date_gmt":"2022-11-09T06:10:58","guid":{"rendered":"https:\/\/hic.nycu.edu.tw\/?page_id=78"},"modified":"2026-05-21T01:00:54","modified_gmt":"2026-05-20T17:00:54","slug":"%e7%a0%94%e7%a9%b6%e6%88%90%e6%9e%9c","status":"publish","type":"page","link":"https:\/\/hic.nycu.edu.tw\/eng\/%e7%a0%94%e7%a9%b6%e6%88%90%e6%9e%9c\/","title":{"rendered":"RESEARCH RESULTS"},"content":{"rendered":"\n
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\u7814\u7a76\u91cd\u9ede<\/strong><\/p>\n

\u7814\u7a76\u5fae\u83cc\u53e2\u5c0d\u65bc\u6d88\u5316\u7cfb\u764c\u75c7\u3001\u4ee3\u8b1d\u75c7\u5019\u7fa4\u3001\u7f55\u898b\u4ee3\u8b1d\u7570\u5e38\u75be\u75c5\u4e4b\u89d2\u8272\uff0c\u4ee5\u53ca\u5176\u81f4\u75c5\u6a5f\u8f49\uff0c\u4e26\u767c\u5c55\u4ee5\u5fae\u83cc\u53e2\u70ba\u6838\u5fc3\u7684\u751f\u7269\u6a19\u8a18\u53ca\u4ecb\u5165\u7b56\u7565\u3002
\u4ee5\u5fae\u83cc\u53e2\u70ba\u6838\u5fc3\uff0c\u7814\u7a76\u4e0a\u8ff0\u75be\u75c5\u53ca\u5176\u4e9e\u5065\u5eb7\u65cf\u7fa4\u4e4b\u591a\u9ad4\u5b78\u53ca\u8868\u578b\u7d44\u5b78\uff0c\u4e26\u5efa\u7acb\u5176\u6578\u4f4d\u5206\u8eab\uff0c\u4ee5\u9032\u884c\u75be\u75c5\u7684\u9810\u6e2c\u53ca\u9810\u9632\u3002
\u4ee5\u4e0a\u8ff0\u7814\u7a76\u4f86\u767c\u5c55\u7cbe\u6e96\u5065\u5eb7\u7684\u7522\u3001\u5b78\u3001\u7814\u4e4b\u7814\u767c\u751f\u614b\u93c8\uff0c\u62d3\u5c55\u5f9e\u57fa\u790e\u5230\u81e8\u5e8a\u3001\u5be6\u9a57\u5ba4\u5230\u75c5\u623f\u7167\u8b77\u3001\u91ab\u9662\u5230\u793e\u5340\u7684\u7522\u5b78\u5275\u65b0\u7814\u767c\u50f9\u503c\u3002<\/p><\/strong><\/cite><\/blockquote>\n\n\n\n

\u8fd1\u671f\u671f\u520a\u8ad6\u6587\u767c\u8868<\/strong><\/p>\n\n\n\n

\u767c\u8868\u65e5\u671f<\/td>\u4f5c\u8005<\/td>\u8ad6\u6587\u540d\u7a31<\/td>\u6458\u8981<\/td>\u671f\u520a\u540d\u7a31<\/td>SCI Impact Factor<\/td><\/tr>
2026\u5e743\u6708<\/td>\u5433\u8389\u73b2\u52a9\u7406\u6559\u6388\u7b49\u4eba<\/td>Nfil3 integrates circadian rhythm and microbial metabolite signaling to maintain gut-liver immune-metabolic homeostasis under high-fat diet stress.<\/a><\/td>\u88dc\u5145\u76ca\u751f\u83ccVSL#3\u53ef\u6e1b\u8f15\u591a\u7a2eHFD\u76f8\u95dc\u8868\u578b\uff0c\u5305\u62ec\u9ad4\u91cd\u589e\u52a0\u3001\u8461\u8404\u7cd6\u8010\u53d7\u4e0d\u826f\u3001\u8840\u8102\u7570\u5e38\u3001\u8f49\u6c28\u9176\u5347\u9ad8\u3001\u809d\u81df\u8102\u8cea\u84c4\u7a4d\u548c\u8178\u9053\u4e0a\u76ae\u901a\u900f\u6027\u589e\u52a0\uff0c\u4e26\u90e8\u5206\u6062\u5fa9\u809d\u5167\u514d\u75ab\u7d30\u80de\u7d44\u6210\u3002<\/td>J Transl Med<\/td>7.5<\/td><\/tr>
2026\u5e743\u6708<\/td>\u5f35\u5a77\u5a77\u526f\u6559\u6388\u7b49\u4eba<\/td>CCL7 suppression alleviates vascular injury by blocking the CCR5\/STAT1 signaling pathway in chronic kidney disease<\/a><\/td>\u6162\u6027\u814e\u81df\u75c5\uff08CKD\uff09\u60a3\u8005\u7f79\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u98a8\u96aa\u986f\u8457\u589e\u52a0\u3002<\/td>Life Sciences<\/td>5.1<\/td><\/tr>
2026\u5e743\u6708<\/td>\u694a\u6bc5\u8f1d\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol-Associated Cirrhosis<\/a><\/td>\u914d\u5c0d\u5f8c\uff0c\u5171\u5206\u6790\u4e86571\u4f8b\u5df4\u6c2f\u82ac\u8d77\u59cb\u6cbb\u7642\u60a3\u8005\u548c571\u4f8b\u963f\u574e\u9178\u8d77\u59cb\u6cbb\u7642\u60a3\u8005\u3002\u5df4\u6c2f\u82ac\u7d441\u5e74\u5167\u767c\u751fMALO\u7684\u6a5f\u7387\uff0834.3%\uff09\u9ad8\u65bc\u963f\u574e\u9178\u7d44\uff0827.4%\uff09\uff0c\u98a8\u96aa\u6bd4\uff08HR\uff09\u70ba1.32\uff0895% CI\uff0c1.02-1.70\uff09\u3002\u5728\u5404\u9805\u4e8b\u4ef6\u4e2d\uff0c\u5df4\u6c2f\u82ac\u8207\u809d\u6027\u8166\u75c5\u8b8a\u98a8\u96aa\u5347\u9ad8\u76f8\u95dc\uff08HR 1.80\uff1b95% CI\uff0c1.21-2.69\uff09\u3002\u5176\u4ed6\u5404\u9805\u4e8b\u4ef6\u6216\u6b7b\u4ea1\u7387\u672a\u898b\u986f\u8457\u5dee\u7570\u3002\u4e9e\u7d44\u5206\u6790\u63d0\u793a\uff0c56-70\u6b72\u60a3\u8005\u7684\u98a8\u96aa\u8f03\u9ad8\u3002<\/td>Aliment Pharmacol Ther<\/td>6.7<\/td><\/tr>
2026\u5e743\u6708<\/td>
\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>		Real-World Safety of JAK Inhibitors in Skin Immune-Mediated Inflammatory Diseases: Boxed Warning Outcomes from a Multinational Cohort Study.<\/a><\/td>\u5728\u76ae\u819a\u514d\u75ab\u4ecb\u5c0e\u767c\u708e\u6027\u75be\u75c5\uff08IMID\uff09\u60a3\u8005\u4e2d\uff0c\u8207\u50b3\u7d71\u5168\u8eab\u6027\u85e5\u7269\u76f8\u6bd4\uff0cJAK\u6291\u5236\u5291\u57282\u5e74\u5167\u4e0d\u6703\u589e\u52a0\u6b7b\u4ea1\u7387\u3001\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff09\u3001\u975c\u8108\u8840\u6813\u6813\u585e\u6216\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\u3002<\/td>Clin Pharmacol Ther<\/td>5.5<\/td><\/tr>
2026\u5e743\u6708<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Validated nationwide scoring system for hepatocellular carcinoma risk in metabolic dysfunction-associated steatotic liver disease.<\/a><\/td>CAMD\u8a55\u5206\u662f\u4e00\u7a2e\u6613\u65bc\u8a08\u7b97\u7684\u5de5\u5177\uff0c\u53ef\u4ee5\u4fc3\u9032MASLD\u60a3\u8005\u7684\u5927\u898f\u6a21HCC\u76e3\u6e2c\u3002<\/td>Liver International<\/td>5.2<\/td><\/tr>
2026\u5e743\u6708<\/td>\u6881\u7acb\u9716\u526f\u6559\u6388\u7b49<\/td>Mandated capacity reductions created new gender disparities in liver cancer surveillance: a population-based cohort study<\/a><\/td>\u5373\u4f7f\u5728\u65b0\u51a0\u80ba\u708e\u75c5\u4f8b\u6975\u5c11\u7684\u60c5\u6cc1\u4e0b\uff0c\u653f\u5e9c\u5f37\u5236\u524a\u6e1b\u91ab\u7642\u8cc7\u6e90\u4e5f\u5c0e\u81f4\u4e86\u56b4\u91cd\u7684\u3001\u9577\u671f\u7684\u76e3\u6e2c\u6f0f\u6d1e\u3002\u9019\u4e9b\u653f\u7b56\u9020\u6210\u4e86\u65b0\u7684\u3001\u6301\u7e8c\u5b58\u5728\u7684\u6027\u5225\u4e0d\u5e73\u7b49\uff0c\u4e26\u8207\u5168\u6c11\u5065\u4fdd\u9ad4\u7cfb\u5167\u764c\u75c7\u7be9\u6aa2\u7684\u5ef6\u8aa4\u6709\u95dc\u3002\u5371\u6a5f\u61c9\u8b8a\u8a08\u756b\u5fc5\u9808\u7d0d\u5165\u5065\u5eb7\u516c\u5e73\u5f71\u97ff\u8a55\u4f30\uff0c\u4ee5\u9632\u6b62\u9020\u6210\u610f\u60f3\u4e0d\u5230\u7684\u50b7\u5bb3\u3002\u8feb\u5207\u9700\u8981\u88fd\u5b9a\u6027\u5225\u654f\u611f\u7b56\u7565\uff0c\u4ee5\u91cd\u65b0\u5438\u5f15\u5973\u6027\u53c3\u8207\u9810\u9632\u4fdd\u5065\u3002<\/td>International Journal for Equity in Health<\/td>4.1<\/td><\/tr>
2026\u5e742\u6708<\/td>\u5433\u8389\u73b2\u52a9\u7406\u6559\u6388\u7b49<\/td>Cumulative defined daily doses Enables Objective Assessment of Treatment Intensity and Outcome Prediction in IgG4-RD and Its subtypes<\/a><\/td>\u4e0d\u540c\u7684\u589e\u6b96\u578b\u548c\u7e96\u7dad\u5316\u578b\u8868\u578b\u8868\u73fe\u51fa\u4e0d\u540c\u7684\u98a8\u96aa\u548c\u6cbb\u7642\u53cd\u61c9\u3002\u5b9a\u91cfcDDD\u8a55\u4f30\u80fd\u5920\u5ba2\u89c0\u8a55\u4f30\u6cbb\u7642\u5f37\u5ea6\u548c\u9810\u6e2c\u7642\u6548\uff0c\u5f9e\u800c\u652f\u6301\u91dd\u5c0dIgG4\u76f8\u95dc\u75be\u75c5\u5206\u671f\u7684\u7cbe\u6e96\u6cbb\u7642\u65b9\u6848\u3002<\/td>Rheumatology<\/td>4.4<\/td><\/tr>
2026\u5e742\u6708<\/td>\u5f35\u5a77\u5a77\u526f\u6559\u6388\u7b49<\/td>Inhibition of CCL4 prevents renal inflammation and fibrosis in acute kidney injury.<\/a><\/td>\u6025\u6027\u814e\u640d\u50b7\uff08AKI\uff09\u662f\u4e00\u7a2e\u81e8\u5e8a\u4e0a\u5e38\u898b\u7684\u75be\u75c5\uff0c\u8207\u9ad8\u767c\u75c5\u7387\u548c\u9ad8\u6b7b\u4ea1\u7387\u76f8\u95dc\uff0c\u5176\u4e2d\u7f3a\u8840\/\u518d\u704c\u6ce8\uff08I\/R\uff09\u548c\u81bf\u6bd2\u75c7\u5f15\u8d77\u7684AKI\u5c24\u70ba\u5e38\u898b\u3002\u8da8\u5316\u56e0\u5b50CC\u57fa\u5e8f\u914d\u9ad44\uff08CCL4\uff09\u662f\u4e00\u7a2e\u4fc3\u767c\u708e\u8da8\u5316\u56e0\u5b50\uff0c\u5728\u814e\u81df\u75be\u75c5\u4e2d\u8868\u9054\u4e0a\u8abf\u3002\u672c\u7814\u7a76\u63a2\u8a0e\u4e86CCL4\u5728AKI\u767c\u75c5\u6a5f\u5236\u4e2d\u7684\u4f5c\u7528\uff0c\u91cd\u9ede\u5728\u65bc\u5176\u900f\u904e\u8a0a\u865f\u50b3\u5c0e\u548c\u8f49\u9304\u6d3b\u5316\u56e0\u5b503\uff08STAT3\uff09\u8a0a\u865f\u8def\u5f91\u8abf\u7bc0\u767c\u708e\u548c\u7e96\u7dad\u5316\u53cd\u61c9\u7684\u6f5b\u529b\u3002\u7d50\u679c\u63d0\u793aCCL4\u5728AKI\u7684\u75c5\u7406\u751f\u7406\u904e\u7a0b\u4e2d\u767c\u63ee\u95dc\u9375\u4f5c\u7528\uff0c\u5c24\u5176\u662f\u5728STAT3\u8abf\u63a7\u767c\u708e\u548c\u7e96\u7dad\u5316\u904e\u7a0b\u4e2d\u3002\u6211\u5011\u7684\u7814\u7a76\u7d50\u679c\u63d0\u793a\uff0c\u9776\u5411CCL4\u53ef\u80fd\u70ba\u7de9\u89e3AKI\u4e26\u9810\u9632\u5176\u9032\u5c55\u70ba\u6162\u6027\u814e\u81df\u75c5\u63d0\u4f9b\u4e00\u7a2e\u65b0\u7684\u6cbb\u7642\u65b9\u6cd5\u3002<\/td>Clinical Science<\/td>7.7<\/td><\/tr>
2026\u5e742\u6708<\/td>\u5433\u8389\u73b2\u52a9\u7406\u6559\u6388\u7b49<\/td>Comparative analysis of renal dysfunction, immune remodeling, and gut microbiota profiles in dietary models of metabolic liver disease<\/a><\/td>\u4e0d\u540c\u7684\u71df\u990a\u6210\u5206\u5728\u8178-\u809d-\u814e\u8ef8\u4e0a\u5f15\u767c\u4e86\u4e0d\u540c\u7684\u514d\u75ab\u4ee3\u8b1d\u548c\u5fae\u751f\u7269\u53cd\u61c9\u3002\u9ad8\u8102\u98f2\u98df\uff08HFD\uff09\u548c\u4f4e\u8102\u9ad8\u7cd6\u98f2\u98df\uff08CDAHFD\uff09\u5728\u5c0f\u9f20\u4e2d\u7522\u751f\u4e86\u4e0d\u540c\u7684\u809d\u81df\u3001\u814e\u81df\u3001\u514d\u75ab\u548c\u5fae\u751f\u7269\u8868\u578b\uff0c\u986f\u793a\u5176\u4ee3\u8b1d\u640d\u50b7\u6a5f\u5236\u7368\u7279\uff0c\u800c\u975e\u75be\u75c5\u7684\u540c\u6b65\u968e\u6bb5\u3002\u5118\u7ba1\u672a\u76f4\u63a5\u8a55\u4f30\u5668\u5b98\u9593\u7684\u6a5f\u5236\u6027\u901a\u8a0a\uff0c\u4f46\u6b64\u6bd4\u8f03\u6846\u67b6\u5f37\u8abf\u4e86\u5728\u89e3\u91cb\u5be6\u9a57\u6027MASLD\u6a21\u578b\u7684\u591a\u5668\u5b98\u7d50\u5c40\u6642\uff0c\u98f2\u98df\u6210\u5206\u548c\u640d\u50b7\u52d5\u529b\u5b78\u7684\u91cd\u8981\u6027\u3002<\/td>BMC Nephrology<\/td>2.4<\/td><\/tr>
2026\u5e742\u6708<\/td>\u5433\u8389\u73b2\u52a9\u7406\u6559\u6388\u7b49<\/td>FK506-binding protein five deficiency influences gut microbiota, gut barrier, and hepatic immune-metabolic coordination in high fat diet-induced metabolic-associated fatty liver disease<\/a><\/td>KBP5\u6709\u52a9\u65bc\u8178\u9053\u83cc\u53e2\u61c9\u5c0d\u514d\u75ab\u53cd\u61c9\u4e0d\u8db3\u7684\u554f\u984c\uff0c\u4e26\u900f\u904e\u6539\u5584\u8178\u9053\u83cc\u53e2\u5c0dHFD\u8a98\u5c0e\u7684\u4ee3\u8b1d\u76f8\u95dc\u8102\u80aa\u809d\uff08MASLD\uff09\u7684\u53cd\u61c9\u4f86\u62b5\u6297\u80a5\u80d6\u3002 <\/td>Scientific Reports<\/td>3.9<\/td><\/tr>
2026\u5e742\u6708<\/td>Chen CJ\u8207\u9ad8\u6b63\u5f65\u526f\u6559\u6388\u7b49<\/td>Genotypes, antibiotic resistance, and virulence diversity among Klebsiella pneumoniae species complex isolates in Taiwan.<\/a><\/td>\u80ba\u708e\u514b\u96f7\u4f2f\u83cc\uff08K. pneumoniae\uff09<\/em>\u3001\u64ec\u80ba\u708e
\u514b\u96f7\u4f2f\u83cc\uff08K. quasipneumoniae<\/em> \uff09\u548c
\u8b8a\u7570\u514b\u96f7\u4f2f\u83cc\uff08K. variicola\uff09\u8868\u73fe\u51fa\u4e0d\u540c\u7684\u57fa\u56e0\u578b\u548c\u8868\u578b\u7279\u5fb5\u3002<\/em>\u64ec\u80ba\u708e\u514b\u96f7\u4f2f\u83cc<\/em>\u548c\u8b8a\u7570\u514b\u96f7\u4f2f\u83cc<\/em>\u5728\u5e7c\u87f2\u611f\u67d3\u6a21\u578b\u4e2d\u8868\u73fe\u51fa\u66f4\u9ad8\u7684\u6b7b\u4ea1\u7387\uff0c\u9019\u51f8\u986f\u4e86\u6301\u7e8c\u76e3\u6e2c\u5176\u50b3\u64ad\u7684\u91cd\u8981\u6027\u3002<\/td>		Gut Pathogens<\/td>4<\/td><\/tr>
2026\u5e742\u6708<\/td>\u9673\u6021\u5982, \u4f55\u79c0\u69ae, \u66fe\u666f\u9d3b, Chen YF, Shieh JJ, \u5433\u4fca\u7a4e<\/td>Akkermansia muciniphila ameliorates imiquimod-induced skin thickening, colitis, and gut microbiota alterations: a metagenome association study.<\/a><\/td>pAkk\u53ef\u80fd<\/em>\u6e1b\u8f15IMQ\u5f15\u8d77\u7684\u76ae\u819a\u589e\u539a\u548cDSS\u8a98\u5c0e\u7684\u7d50\u8178\u708e\uff0c\u4e26\u4f34\u96a8TNF-\u03b1\u548cIL-17A\u6c34\u5e73\u964d\u4f4e\u3002 p Akk<\/em>\u88dc\u5145\u5291\u53ef\u6539\u8b8a IMQ \u6cbb\u7642\u5c0f\u9f20\u7684\u7cde\u4fbf\u5fae\u751f\u7269\u7fa4\u548c\u4ee3\u8b1d\u9014\u5f91\u3002<\/td>Inflammation<\/td>5<\/td><\/tr>
2026\u5e742\u6708<\/td>Duong TTT\u8207\u9ad8\u6b63\u5f65\u526f\u6559\u6388\u7b49<\/td>A combined genetic and phenotypic marker approach enables precise detection of hypervirulent Klebsiella pneumoniae and reveals associated traits of capsule overproduction and tellurite resistance.<\/a><\/td>\u672c\u7814\u7a76\u6574\u5408\u57fa\u56e0\u578b\u8207\u8868\u73fe\u578b\u5206\u6790\uff0c\u627e\u51fa\u53ef\u5075\u6e2c\u9ad8\u6bd2\u529b\u80ba\u708e\u514b\u96f7\u4f2f\u6c0f\u83cc\uff08hvKp\uff09\u7684\u751f\u7269\u6a19\u8a18\uff0c\u7d50\u679c\u986f\u793a\u7d50\u5408\u4e94\u7a2e\u6bd2\u529b\u57fa\u56e0\uff08peg-344\u3001iroB\u3001iucA\u3001rmpA\u3001rmpA2\uff09\u8a66\u9a57\uff0c\u53ef\u6709\u6548\u5340\u5206 hvKp\uff0c\u4e14\u8207\u8f03\u9ad8\u7684\u83a2\u819c\u7522\u91cf\u53ca\u6bd2\u529b\u5bc6\u5207\u76f8\u95dc\u3002<\/td>Microbiol Spectr<\/td>3.8<\/td><\/tr>
2026\u5e742\u6708<\/td>Yueh-Jung Chao\u8207\u9ad8\u6b63\u5f65\u526f\u6559\u6388\u7b49\u4eba<\/td>Hha toxin regulates diverse phenotypes of uropathogenic Proteus mirabilis including virulence<\/a><\/td>\u5947\u7570\u8b8a\u5f62\u687f\u83cc\u6bd2\u7d20-\u6297\u6bd2\u7d20\u7cfb\u7d71\uff08TA\uff09\u4e2d\u7684Hha\u86cb\u767d\u53c3\u8207\u5176\u6bd2\u529b\uff0c\u4e26\u53d7\u9285\u96e2\u5b50\u654f\u611f\u53d7\u9ad4CpxR\u7684\u8abf\u63a7\u3002\u672c\u7814\u7a76\u986f\u793aHha\u86cb\u767d\u53ef\u4f5c\u70ba\u6cbb\u7642\u5947\u7570\u8b8a\u5f62\u687f\u83cc\u6ccc\u5c3f\u9053\u611f\u67d3\u7684\u6f5b\u5728\u85e5\u7269\u9776\u9ede\uff0c\u4e26\u70ba\u7814\u7a76TA\u7cfb\u7d71\u4ee5\u63a7\u5236\u7d30\u83cc\u6bd2\u529b\u958b\u95e2\u4e86\u65b0\u7684\u8996\u89d2\u3002<\/td>J Microbiol Immunol Infect<\/td>3.7<\/td><\/tr>
2026\u5e742\u6708<\/td>Wu-Chun Chung\u8207\u6d2a\u54f2\u502b\u6559\u6388\u7b49\u4eba<\/td>Decentralized Federated Learning with Non-IID Data: Challenges, Trends, and Future Opportunities<\/a><\/td>\u672c\u6587\u5c0d\u975e\u7368\u7acb\u540c\u5206\u4f48\u74b0\u5883\u4e0b\u7684\u53bb\u4e2d\u5fc3\u5316\u806f\u90a6\u5b78\u7fd2\u7814\u7a76\u9032\u884c\u4e86\u7cfb\u7d71\u6027\u6587\u737b\u56de\u9867\uff08SLR\uff09\uff0c\u900f\u904e\u5c0d\u6587\u737b\u3001\u5be6\u9a57\u8a2d\u7f6e\u548c\u8a55\u4f30\u5be6\u8e10\u9032\u884c\u7d50\u69cb\u5316\u5206\u6790\uff0c\u672c\u6587\u91cd\u9ede\u95e1\u8ff0\u4e86\u95dc\u9375\u8da8\u52e2\uff0c\u63ed\u793a\u4e86\u7814\u7a76\u7a7a\u767d\uff0c\u4e26\u70ba\u5728\u975e\u7368\u7acb\u540c\u5206\u4f48\u74b0\u5883\u4e0b\u63a8\u9032\u8a2d\u8a08\u5b78\u7fd2\uff08DFL\uff09\u63d0\u51fa\u4e86\u672a\u4f86\u65b9\u5411\u3002<\/td>ACM Computing Surveys<\/td>28<\/td><\/tr>
2026\u5e741\u6708<\/td>Zhang M\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Unbiased clustering of acute-on-chronic liver failure patients using machine learning in a real-world ICU cohort.<\/a><\/td>\u672c\u7814\u7a76\u4ee5\u7121\u76e3\u7763\u5206\u7fa4\u65b9\u6cd5\u5206\u67901,256\u540d\u6025\u6027\u52a0\u91cd\u578b\u6162\u6027\u809d\u8870\u7aed\uff08ACLF\uff09\u60a3\u8005\uff0c\u6210\u529f\u8b58\u5225\u51fa\u5169\u500b\u81e8\u5e8a\u7279\u5fb5\u660e\u986f\u4e0d\u540c\u7684\u65cf\u7fa4\uff0c\u517630\u5929\u6b7b\u4ea1\u7387\u5dee\u7570\u986f\u8457\uff08\u7d0470% vs 26%\uff09\u3002
\u7d50\u679c\u986f\u793a\u9178\u9e7c\u5e73\u8861\u76f8\u95dc\u6307\u6a19\uff08\u5982\u78b3\u9178\u6c2b\u9e7d\u3001pH\u3001\u4e73\u9178\u8207\u9670\u96e2\u5b50\u9593\u9699\uff09\u70ba\u95dc\u9375\u5206\u7fa4\u56e0\u5b50\uff0c\u4e14\u7d93\u5916\u90e8\u9a57\u8b49\u652f\u6301\u5176\u5728\u9810\u6e2c\u9810\u5f8c\u8207\u98a8\u96aa\u5206\u5c64\u4e2d\u7684\u91cd\u8981\u6027\u3002<\/td>		Nature Communication<\/td>15.7<\/td><\/tr>
2026\u5e741\u6708<\/td>Fan YH\u8207\u9ad8\u6b63\u5f65\u526f\u6559\u6388\u7b49\u4eba<\/td>Emergence of conjugative metallo-\u03b2-lactamase-encoding plasmids in the Klebsiella pneumoniae species complex: First identification of IMP-8-MCR-9.1 in K. quasipneumoniae and VIM-1 in K. variicola in Taiwan<\/a><\/td>\u672c\u7814\u7a76\u9996\u6b21\u5728\u53f0\u7063\u5831\u544aKq\u8207Kv\u4e2d\u5b58\u5728\u53ef\u50b3\u64ad\u7684\u78b3\u9752\u9ef4\u70ef\u9176\u8cea\u9ad4\uff0c\u5176\u91cd\u7d44\u8207\u64f4\u6563\u60c5\u5f62\u503c\u5f97\u6301\u7e8c\u5bc6\u5207\u76e3\u6e2c\u3002<\/td>Journal of Infection and Public Health<\/td>4<\/td><\/tr>
2026\u5e741\u6708<\/td>\u694a\u6bc5\u8f1d\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Dynamic FIB-4 score changes and HCC risk in patients with MASLD and elevated liver enzymes: a nationwide cohort study.<\/a><\/td>\u9023\u7e8c\u8ffd\u8e64FIB-4 score\u8b8a\u5316\u6bd4\u55ae\u6b21\u6e2c\u91cf\u66f4\u80fd\u6e96\u78ba\u9810\u6e2c\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u98a8\u96aa\uff0c\u5728\u7121\u809d\u786c\u5316\u4e14\u809d\u9175\u7d20\u5347\u9ad8\u7684MASLD\u4e9e\u6d32\u65cf\u7fa4\u4e2d\uff0c\u5b9a\u671fFIB-4\u76e3\u6e2c\u6709\u52a9\u65bc\u8fa8\u8b58\u9ad8\u98a8\u96aa\u65cf\u7fa4\u3002<\/td>Liver Cancer<\/td>9.1<\/td><\/tr>
2026\u5e741\u6708<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Psoriatic arthritis risk in psoriasis patients receiving anti-IL-23 vs anti-IL-17: comparison of drug classes and individual agents.<\/a><\/td>\u76f8\u8f03\u65bcIL17\u6291\u5236\u5291\uff08IL17i\uff09\uff0c\u4f7f\u7528IL23\u6291\u5236\u5291\uff08IL23i\uff09\u7684\u4e7e\u766c\uff08PsO\uff09\u60a3\u8005\u57285\u5e74\u5167\u767c\u751f\u4e7e\u766c\u6027\u95dc\u7bc0\u708e\uff08PsA\uff09\u7684\u98a8\u96aa\u986f\u8457\u8f03\u4f4e\uff0c\u4e14\u6b64\u5dee\u7570\u5728\u4e0d\u540c\u5e74\u9f61\u3001\u6027\u5225\u3001\u7a2e\u65cf\u53ca\u81e8\u5e8a\u4e9e\u7fa4\u4e2d\u7686\u4e00\u81f4\u3002
\u7d50\u8ad6\u6307\u51fa\uff0cIL23i\u6cbb\u7642\u8207\u8f03\u4f4e\u7684PsA\u767c\u751f\u98a8\u96aa\u76f8\u95dc\uff0c\u512a\u65bcIL17i\uff0c\u986f\u793a\u5176\u5728\u9810\u9632PsA\u65b9\u9762\u53ef\u80fd\u5177\u6709\u6f5b\u5728\u512a\u52e2\u3002<\/td>		Rheumatology<\/td>4.4<\/td><\/tr>
2025\u5e7412\u6708(accepted)<\/td>\u5f35\u5a77\u5a77\u526f\u6559\u6388\u7b49\u4eba<\/td>Sodium nitroprusside improves ischemia-induced neovascularization via the HO-1\/NOX and AKT\/eNOS signaling pathways in chronic kidney disease. Life Sciences.<\/a><\/td>SNP\u6cbb\u7642\u53ef\u4e0a\u8abf\u5faa\u74b0\u4e2d\u7684\u4fc3\u8840\u7ba1\u65b0\u751f\u56e0\u5b50\u3001\u6539\u5584\u8840\u6d41\u6062\u5fa9\u3001\u589e\u52a0\u5fae\u8840\u7ba1\u5bc6\u5ea6\uff0c\u4e26\u9006\u8f49\u7f3a\u8840\u7d44\u7e54\u4e2d\u4fc3\u8840\u7ba1\u65b0\u751f\u8207\u767c\u708e\u86cb\u767d\u7684\u8868\u73fe\uff0c\u4f46\u672a\u80fd\u6062\u5fa9\u6162\u6027\u814e\u81df\u75c5\uff08CKD\uff09\u5c0f\u9f20\u7684\u814e\u529f\u80fd\u3002\u672c\u7814\u7a76\u70ba\u5728\u5408\u4f75\u8840\u7ba1\u4f75\u767c\u75c7\u7684\u6162\u6027\u814e\u81df\u75c5\uff08CKD\uff09\u60a3\u8005\u4e2d\uff0c\u4f7f\u7528SNP\u4f5c\u70ba\u6f5b\u5728\u6cbb\u7642\u4ecb\u5165\u63d0\u4f9b\u4e86\u7406\u8ad6\u57fa\u790e\u3002<\/td>Life Sciences<\/td>5.1<\/td><\/tr>
2025\u5e7411\u6708(accepted)<\/td>\u694a\u6bc5\u8f1d\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Dynamic FIB-4 score changes and HCC risk in patients with MASLD and elevated liver enzymes: a nationwide cohort study.<\/a><\/td>\u5728\u975e\u809d\u786c\u5316\u4e14\u809d\u9175\u7d20\u5347\u9ad8\u7684MASLD\u65cf\u7fa4\u4e2d\uff0c\u9023\u7e8c\u4e09\u5e74\u8ffd\u8e64FIB-4\u5206\u6578\u8b8a\u5316\u6bd4\u55ae\u6b21\u6e2c\u91cf\u66f4\u80fd\u6e96\u78ba\u9810\u6e2c\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u98a8\u96aa\u3002\u6301\u7e8c\u9ad8FIB-4\u8005\u98a8\u96aa\u6700\u9ad8\uff0c\u800c\u5206\u6578\u60e1\u5316\u8005\u98a8\u96aa\u4e0a\u5347\u3001\u6539\u5584\u8005\u98a8\u96aa\u4e0b\u964d\uff0c\u986f\u793a\u53ef\u7528\u65bc\u7be9\u9078\u9700\u52a0\u5f37\u76e3\u6e2c\u7684\u9ad8\u98a8\u96aa\u65cf\u7fa4\u3002<\/td>Liver Cancer<\/td>9.1<\/td><\/tr>
2025\u5e7411\u6708(accepted)<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u90ed\u6b63\u6d69\u540c\u5b78\u7b49\u4eba<\/td>Increased risk of antimicrobial resistance in patients with cirrhosis and hepatic encephalopathy using rifaximin<\/a><\/td>\u672c\u7bc7\u7814\u7a76\u5728\u8a55\u4f30Rifaximin\u5728\u809d\u786c\u5316\u5408\u4f75\u809d\u6027\u8166\u75c5\u60a3\u8005\u4e2d\u7684\u4f7f\u7528\u662f\u5426\u589e\u52a0\u6297\u751f\u7d20\u6297\u85e5\u6027\u98a8\u96aa\uff0c\u7814\u7a76\u7d50\u679c\u767c\u73fe\uff0cRifaximin\u8207\u6557\u8840\u75c7\u3001\u81ea\u767c\u6027\u7d30\u83cc\u6027\u8179\u819c\u708e\u53ca\u9700\u4f7f\u7528\u6700\u5f8c\u7dda\u6297\u751f\u7d20\u7684\u98a8\u96aa\u589e\u52a0\u76f8\u95dc\u3002<\/td>Nature Communication<\/td>15.7<\/td><\/tr>
2025\u5e7410\u670817\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Psoriatic arthritis risk in psoriasis patients receiving anti-IL-23 vs anti-IL-17: comparison of drug classes and individual agents<\/a><\/td>\u672c\u7814\u7a76\u6bd4\u8f03\u4e7e\u766c\u60a3\u8005\u4f7f\u7528 IL-23 \u6291\u5236\u5291\u8207 IL-17 \u6291\u5236\u5291\u5f8c\u767c\u5c55\u4e7e\u766c\u6027\u95dc\u7bc0\u708e\u7684\u98a8\u96aa\u5dee\u7570\u3002\u5728 1:1 \u914d\u5c0d\u5f8c\u7684 5,490 \u540d\u60a3\u8005\u4e2d\uff0cIL-23 \u6291\u5236\u5291\u4f7f\u7528\u8005\u7684 5 \u5e74\u4e7e\u766c\u6027\u95dc\u7bc0\u708e\u7d2f\u7a4d\u767c\u751f\u7387\u660e\u986f\u8f03\u4f4e\uff0811.68% vs 19.94%\uff09\uff0c\u98a8\u96aa\u6bd4\u70ba 0.475\u3002\u591a\u9805\u5b50\u65cf\u7fa4\u8207\u500b\u5225\u85e5\u7269\u6bd4\u8f03\u5747\u5448\u73fe\u76f8\u540c\u8da8\u52e2\uff0c\u986f\u793a IL-23 \u6291\u5236\u5291\u76f8\u8f03\u65bc IL-17 \u6291\u5236\u5291\u66f4\u80fd\u964d\u4f4e\u4e7e\u766c\u60a3\u8005\u5f8c\u7e8c\u767c\u5c55\u95dc\u7bc0\u708e\u7684\u98a8\u96aa\u3002<\/td>Rheumatology<\/td>4.4<\/td><\/tr>
2025\u5e7410\u670811\u65e5<\/td>\u66fe\u666f\u9d3b\u535a\u58eb\u8207\u5433\u4fca\u7a4e\u6559\u6388<\/td>From dysbiosis to longevity: a narrative review into the gut microbiome\u2019s impact on aging.<\/a><\/td>\u8178\u9053\u5fae\u751f\u7269\u7d44\u662f\u5f71\u97ff\u8001\u5316\u7684\u91cd\u8981\u4e14\u53ef\u8abf\u63a7\u56e0\u7d20\uff0c\u52d5\u7269\u5be6\u9a57\u8b49\u5be6\u5176\u53ef\u56e0\u679c\u6027\u5730\u5f71\u97ff\u58fd\u547d\u8207\u8001\u5316\u9032\u7a0b\u3002\u4eba\u9ad4\u8178\u9053\u83cc\u76f8\u96a8\u5e74\u9f61\u3001\u98f2\u98df\u3001\u751f\u6d3b\u578b\u614b\u3001\u8377\u723e\u8499\u8207\u514d\u75ab\u529f\u80fd\u800c\u6f14\u8b8a\uff0c\u4e26\u900f\u904e\u8178\u9053\uff0d\u808c\u8089\u8207\u8178\u9053\uff0d\u5927\u8166\u8ef8\u8abf\u7bc0\u665a\u5e74\u7684\u5065\u5eb7\u72c0\u614b\uff1b\u9577\u58fd\u8005\u901a\u5e38\u5177\u6709\u8f03\u9ad8\u591a\u6a23\u6027\u8207\u66f4\u4f73\u7684\u8178\u9053\u7a69\u614b\u3002\u9ad8\u7e96\u98f2\u98df\u3001\u898f\u5f8b\u904b\u52d5\u53ca\u76ca\u751f\u83cc\uff0f\u76ca\u751f\u5143\uff0f\u5f8c\u751f\u5143\u7b49\u4ecb\u5165\u53ef\u80fd\u4fc3\u9032\u5065\u5eb7\u8001\u5316\uff0c\u672a\u4f86\u4ecd\u9700\u66f4\u591a\u7814\u7a76\u4ee5\u512a\u5316\u76f8\u95dc\u7b56\u7565\u3002<\/td>J Biomed Sci<\/td>12.1<\/td><\/tr>
2025\u5e7409\u670805\u65e5<\/td>\u5289\u5fd7\u9298\u91ab\u5e2b\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Screening and eradication of Helicobacter pylori for gastric cancer prevention: Taipei Global Consensus II.<\/a><\/td>\u570b\u969b\u5c08\u5bb6\u5718\u968a\u900f\u904e GRADE \u8207 Delphi \u65b9\u6cd5\u9054\u6210 28 \u9805\u5171\u8b58\uff0c\u78ba\u8a8d\u5e7d\u9580\u87ba\u65cb\u687f\u83cc\u6839\u9664\u53ef\u6709\u6548\u964d\u4f4e\u6240\u6709\u5e74\u9f61\u5c64\u7684\u80c3\u764c\u98a8\u96aa\uff0c\u5c24\u5176\u5728\u524d\u764c\u8b8a\u767c\u751f\u524d\u6548\u679c\u6700\u4f73\u3002\u5171\u8b58\u5efa\u8b70\u512a\u5148\u7be9\u6aa2\u9ad8\u98a8\u96aa\u65cf\u7fa4\uff0c\u63a1\u7528 13C \u547c\u6c23\u8a66\u9a57\u6216\u55ae\u682a\u7cde\u4fbf\u6297\u539f\u6aa2\u6e2c\uff0c\u4e26\u5728\u6297\u751f\u7d20\u6297\u85e5\u6027\u9ad8\u7684\u5730\u5340\u4f7f\u7528\u924d\u56db\u806f\u7642\u6cd5\u7b49\u7d93\u9a57\u6027\u6cbb\u7642\uff0c\u6cbb\u7642\u5f8c\u9808\u9032\u884c\u78ba\u8a8d\u6aa2\u6e2c\u3002
\u672a\u4f86\u7814\u7a76\u61c9\u81f4\u529b\u65bc\u91d0\u6e05\u6700\u4f73\u7be9\u6aa2\u6642\u6a5f\u3001\u6cbb\u7642\u5c0d\u5fae\u751f\u7269\u7d44\u53ca\u6297\u85e5\u6027\u7684\u9577\u671f\u5f71\u97ff\uff0c\u4ee5\u53ca\u767c\u5c55\u75ab\u82d7\u8207\u66f4\u7cbe\u6e96\u7684\u500b\u5225\u5316\u98a8\u96aa\u5206\u5c64\u7b56\u7565\u3002<\/td>		Gut<\/td>25.8<\/td><\/tr>
2025\u5e7409\u670801\u65e5<\/td>\u694a\u6bc5\u8f1d\u8207\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Predictive machine learning model in intensive care unit patients with acute-on-chronic liver failure and two or more organ failures<\/a><\/td>\u672c\u7814\u7a76\u5229\u7528\u5927\u578b\u52a0\u8b77\u75c5\u623f\u8cc7\u6599\u5eab\uff0c\u5efa\u7acb\u4e26\u89e3\u91cb\u53ef\u9810\u6e2c\u5177\u5169\u500b\u4ee5\u4e0a\u5668\u5b98\u8870\u7aed\u4e4b\u6025\u6027\u767c\u4f5c\u6162\u6027\u809d\u8870\u7aed\u60a3\u8005 30 \u5929\u6b7b\u4ea1\u7387\u7684\u6a5f\u5668\u5b78\u7fd2\u6a21\u578b\u3002CatBoost \u8207 Random Forest \u5206\u5225\u5728 NACSELD \u8207 EASL-CLIF \u5206\u985e\u4e2d\u9054\u5230\u6700\u4f73\u8868\u73fe\uff08AUC 0.87 \u8207 0.83\uff09\uff0c\u4e14\u6a21\u578b\u7d93 SHAP \u5206\u6790\u89e3\u91cb\u4e26\u7c21\u5316\u5f8c\u4ecd\u7dad\u6301\u9ad8\u6e96\u78ba\u5ea6\uff0c\u512a\u65bc\u73fe\u6709\u8a55\u5206\u7cfb\u7d71\u3002\u6b64\u6a21\u578b\u7d93\u5167\u5916\u90e8\u9a57\u8b49\u4e26\u5177\u826f\u597d\u6821\u6b63\u5ea6\uff0c\u4e26\u5df2\u5efa\u7acb\u53ef\u76f4\u63a5\u4f7f\u7528\u7684\u7dda\u4e0a\u9810\u6e2c\u5de5\u5177\uff0c\u6709\u52a9\u65bc\u81e8\u5e8a\u5feb\u901f\u8a55\u4f30\u6b7b\u4ea1\u98a8\u96aa\u3002<\/td>Clin Mol Hepatol<\/td>16.9<\/td><\/tr>
2025\u5e7409\u6708<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u90ed\u6b63\u6d69\u540c\u5b78\u7b49\u4eba<\/td>Composition and metabolomic shifts of the gut microbiome in alcohol-related liver disease.<\/a><\/td>\u9152\u7cbe\u76f8\u95dc\u809d\u75c5\u4e0d\u50c5\u662f\u809d\u81df\u75be\u75c5\uff0c\u4e5f\u6d89\u53ca\u8178\u809d\u8ef8\u529f\u80fd\u5931\u8861\uff0c\u800c\u9152\u7cbe\u5f15\u8d77\u7684\u8178\u9053\u83cc\u76f8\u5931\u8abf\u5728\u5176\u4e2d\u626e\u6f14\u95dc\u9375\u89d2\u8272\u3002\u672c\u6587\u56de\u9867\u9152\u7cbe\u66b4\u9732\u5f8c\u7684\u8178\u9053\u83cc\u76f8\u8b8a\u5316\uff0c\u4ee5\u53ca\u5176\u4ee3\u8b1d\u7269\uff08\u5982\u8102\u80aa\u9178\u3001\u8272\u80fa\u9178\u884d\u751f\u7269\u8207\u6b21\u7d1a\u81bd\u9178\uff09\u5982\u4f55\u5f71\u97ff\u8178\u9053\u5c4f\u969c\u3001\u514d\u75ab\u53cd\u61c9\u8207\u4ee3\u8b1d\u8def\u5f91\uff0c\u9032\u4e00\u6b65\u52a0\u91cd\u809d\u81df\u640d\u50b7\u3002\u900f\u904e\u5148\u9032\u7684\u591a\u91cd\u9ad4\u5b78\u6280\u8853\u8207\u5fae\u751f\u7269\u7d44\u8abf\u63a7\u7b56\u7565\uff0c\u6709\u671b\u6df1\u5165\u89e3\u6790\u83cc\u76f8\u8207\u5bbf\u4e3b\u4ea4\u4e92\u4f5c\u7528\uff0c\u4e26\u70ba\u9152\u7cbe\u76f8\u95dc\u809d\u75c5\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u6a19\u9776\u3002<\/td>J Gastroenterol Hepatol<\/td>3.4<\/td><\/tr>
2025\u5e7408\u670801\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Psoriasis risk in patients with atopic dermatitis treated with dupilumab.<\/a><\/td>\u9019\u9805\u5927\u578b\u56de\u6eaf\u6027\u7814\u7a76\u6bd4\u8f03\u4e86\u7570\u4f4d\u6027\u76ae\u819a\u708e\u60a3\u8005\u4f7f\u7528 dupilumab \u8207\u5176\u4ed6\u5168\u8eab\u6027\u6cbb\u7642\u7684\u5dee\u7570\uff0c\u767c\u73fe dupilumab \u4f7f\u7528\u8005\u7684\u4e7e\u766c\u767c\u751f\u7387\u8f03\u9ad8\u3002
\u5728 3 \u5e74\u8ffd\u8e64\u4e2d\uff0cdupilumab \u7d44\u7684\u4e7e\u766c\u7d2f\u7a4d\u767c\u751f\u7387\u70ba 2.86%\uff0c\u660e\u986f\u9ad8\u65bc\u63a7\u5236\u7d44\u7684 1.79%\uff0c\u98a8\u96aa\u6bd4\u70ba 1.58\u3002
\u96d6\u7136 dupilumab \u8207\u4e7e\u766c\u4e4b\u9593\u5b58\u5728\u76f8\u5c0d\u98a8\u96aa\u589e\u52a0\uff0c\u4f46\u5176\u7d55\u5c0d\u98a8\u96aa\u4e0d\u9ad8\uff08NNH=94\uff09\uff0c\u81e8\u5e8a\u4e0a\u4ecd\u9700\u5728\u6f5b\u5728\u526f\u4f5c\u7528\u8207\u5176\u6cbb\u7642\u6548\u76ca\u9593\u6b0a\u8861\u3002<\/td>		JAMA Dermatology<\/td>11.0<\/td><\/tr>
2025\u5e7405\u670821\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u3001\u6d2a\u54f2\u502b\u6559\u6388\u8207\u9673\u5efa\u5b89\u540c\u5b78\u7b49<\/td>Identifying disinformation on the extended impacts of COVID-19: methodological investigation using a fuzzy ranking ensemble of natural language processing models.<\/a><\/td>\u672c\u7814\u7a76\u958b\u767c\u4e86\u4e00\u5957\u7d50\u5408\u9810\u8a13\u7df4\u8a9e\u8a00\u6a21\u578b\u8207\u6a21\u7cca\u6392\u5e8f\u96c6\u6210\u65b9\u6cd5\u7684\u6df1\u5ea6\u5b78\u7fd2\u67b6\u69cb\uff0c\u7528\u65bc\u5075\u6e2c\u8207\u9577\u671f\u65b0\u51a0\u5f71\u97ff\u76f8\u95dc\u7684\u932f\u8aa4\u8cc7\u8a0a\u3002
\u5be6\u9a57\u7d50\u679c\u986f\u793a\uff0cXLNet \u53ca\u5176\u8207\u5176\u4ed6\u6a21\u578b\u7684\u6a21\u7cca\u6392\u5e8f\u96c6\u6210\u65b9\u6cd5\u7686\u512a\u65bc\u50b3\u7d71\u65b9\u6cd5\uff0c\u6700\u7d42\u53ef\u9054\u5230 93.52% \u7684\u9ad8\u6e96\u78ba\u7387\u3002
\u6b64\u65b9\u6cd5\u8b49\u5be6\u50c5\u4f9d\u8cf4\u6587\u672c\u5167\u5bb9\u5373\u53ef\u6709\u6548\u63d0\u5347\u5047\u65b0\u805e\u5075\u6e2c\u6548\u80fd\uff0c\u4e26\u5c0d\u516c\u5171\u885b\u751f\u653f\u7b56\u8207\u8a0a\u606f\u50b3\u905e\u5177\u6709\u61c9\u7528\u50f9\u503c\u3002<\/td>		J Med Internet Res<\/td>6.0<\/td><\/tr>
2025\u5e7404\u670817\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Cardiovascular disease risk in patients with psoriasis receiving biologics targeting<\/a><\/td>\u672c\u7814\u7a76\u767c\u73fe\uff0c\u76f8\u8f03\u65bc\u53e3\u670d\u85e5\u7269\uff0c\u4f7f\u7528\u751f\u7269\u88fd\u5291\u6cbb\u7642\u7684\u4e7e\u766c\u60a3\u8005\uff0c\u5176\u5fc3\u8840\u7ba1\u75be\u75c5\u98a8\u96aa\u986f\u8457\u8f03\u4f4e\u3002\u7279\u5225\u662f\u4f7f\u7528\u6297TNF-\u03b1\u3001\u6297IL-17\u8207\u6297IL-23\u85e5\u7269\u7684\u60a3\u8005\uff0c\u8207\u8f03\u4f4e\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u98a8\u96aa\u76f8\u95dc\uff0c\u4f46\u6297IL-12\/23\u5247\u7121\u986f\u8457\u5dee\u7570\u3002\u9019\u4e9b\u7d50\u679c\u5728\u4e0d\u540c\u5e74\u9f61\u3001\u6027\u5225\u3001\u5730\u5340\u8207\u5171\u75c5\u65cf\u7fa4\u4e2d\u7686\u5177\u4e00\u81f4\u6027\uff0c\u652f\u6301\u751f\u7269\u88fd\u5291\u5728\u4e7e\u766c\u6cbb\u7642\u4e2d\u5c0d\u5fc3\u8840\u7ba1\u5065\u5eb7\u7684\u6f5b\u5728\u76ca\u8655\u3002<\/td>PLOS Medicine<\/td>10.5<\/td><\/tr>
2025\u5e7404\u670807\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>The development of live biotherapeutic products: a position statement of Asia-Pacific Microbiota Consortium.<\/a><\/td>\u672c\u7814\u7a76\u7531\u4e9e\u592a\u5730\u5340\u7684\u8178\u9053\u83cc\u76f8\u5c08\u5bb6\u5c31\u6d3b\u6027\u751f\u7269\u6cbb\u7642\u7522\u54c1\uff08LBP\uff09\u7684\u958b\u767c\u63d0\u51fa\u5171\u8b58\u5efa\u8b70\uff0c\u6db5\u84cb\u958b\u767c\u52d5\u6a5f\u3001\u524d\u81e8\u5e8a\u7814\u7a76\u8207\u81e8\u5e8a\u6e96\u5099\u4e09\u5927\u9762\u5411\u3002\u5c08\u5bb6\u5efa\u8b70\u512a\u5148\u4f7f\u7528\u4f86\u6e90\u65bc\u4eba\u9ad4\u8207\u98df\u7269\u7684\u83cc\u682a\uff0c\u4e26\u5f37\u8abf\u958b\u767c\u904e\u7a0b\u9700\u56b4\u683c\u9032\u884c\u529f\u80fd\u8a55\u4f30\u3001\u907a\u50b3\u76e3\u63a7\u8207\u5b89\u5168\u6027\u6e2c\u8a66\u3002\u81e8\u5e8a\u8a66\u9a57\u61c9\u7cbe\u5fc3\u8a2d\u8a08\u4e26\u843d\u5be6\u98a8\u96aa\u7ba1\u7406\uff0c\u4ee5\u78ba\u4fdd\u7522\u54c1\u7684\u5b89\u5168\u6027\u8207\u6709\u6548\u6027\u3002<\/td>Gastroenterology & Hepatology<\/td>23.0<\/td><\/tr>
2024\u5e7412\u670823\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u5433\u8c9e\u5b9c\u4e3b\u4efb\u7b49\u4eba<\/td>Association between Air Quality Index and the risk of rosacea: a nationwide population-based cohort study<\/a><\/td>\u672c\u7814\u7a76\u767c\u73fe\u7a7a\u6c23\u54c1\u8cea\u6307\u6578\uff08AQI\uff09\u8207\u9152\u7cdf\u6027\u76ae\u819a\u708e\u7684\u767c\u751f\u98a8\u96aa\u5448\u73fe\u986f\u8457\u6b63\u76f8\u95dc\uff0c\u6bcf\u589e\u52a0\u4e00\u55ae\u4f4dAQI\uff0c\u98a8\u96aa\u4e0a\u53475%\u3002AQI\u8d8a\u9ad8\u7684\u65cf\u7fa4\uff0c\u7f79\u60a3\u9152\u7cdf\u6027\u76ae\u819a\u708e\u7684\u98a8\u96aa\u4e5f\u8d8a\u9ad8\uff0c\u6700\u9ad8\u7d44\u5225\u98a8\u96aa\u9054\u6700\u4f4e\u7d44\u76847.22\u500d\u3002\u7d30\u61f8\u6d6e\u5fae\u7c92\uff08PM2.5\uff09\u3001\u4e8c\u6c27\u5316\u786b\uff08SO\u2082\uff09\u8207\u4e00\u6c27\u5316\u78b3\u66b4\u9732\u6703\u589e\u52a0\u98a8\u96aa\uff0c\u800cPM10\u5247\u8207\u8f03\u4f4e\u98a8\u96aa\u76f8\u95dc\u3002<\/td>Clin Exp Dermatol<\/td>3.7<\/td><\/tr>
2024\u5e7411\u670828\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Dupilumab impact on psychiatric and sleep disorder risk reduction in atopic dermatitis: A population-based cohort study<\/a><\/td>\u672c\u7814\u7a76\u767c\u73fe\uff0c\u76f8\u8f03\u65bc\u50b3\u7d71\u6cbb\u7642\u85e5\u7269\uff0c\u4f7f\u7528Dupilumab\u6cbb\u7642\u7570\u4f4d\u6027\u76ae\u819a\u708e\u7684\u60a3\u8005\u5728\u4e09\u5e74\u5167\u7f79\u60a3\u7126\u616e\u3001\u6182\u9b31\u3001\u9069\u61c9\u969c\u7919\u8207\u7761\u7720\u969c\u7919\u7684\u98a8\u96aa\u986f\u8457\u8f03\u4f4e\u3002\u9019\u4e9b\u7d50\u679c\u5728\u4e0d\u540c\u5e74\u9f61\u3001\u6027\u5225\u3001\u7a2e\u65cf\u8207\u5171\u75c5\u7fa4\u9ad4\u4e2d\u7686\u4e00\u81f4\uff0c\u5c24\u5176\u5728\u975e\u88d4\u7f8e\u570b\u4eba\u65cf\u7fa4\u4e2d\u6548\u679c\u66f4\u70ba\u660e\u986f\u3002\u552f\u6709\u6ce8\u610f\u529b\u4e0d\u8db3\u904e\u52d5\u75c7\u7684\u98a8\u96aa\u5dee\u7570\u4e0d\u5177\u7d71\u8a08\u986f\u8457\u6027\u3002<\/td>Ann Allergy Asthma Immunol<\/td>5.8<\/td><\/tr>
2024\u5e7411\u670825\u65e5<\/td>\u6881\u7acb\u9716\u526f\u6559\u6388\u7b49\u4eba<\/td>Taiwan case study: balancing health and economy during COVID-19.<\/a><\/td>\u672c\u7814\u7a76\u8a55\u4f30\u4e86\u53f0\u7063\u653f\u5e9c\u5728COVID-19\u75ab\u60c5\u671f\u9593\u65bc\u5065\u5eb7\u3001\u7d93\u6fdf\u8207\u793e\u6703\u4e09\u65b9\u9762\u7684\u61c9\u5c0d\u8207\u8868\u73fe\u3002\u53f0\u7063\u521d\u671f\u9632\u75ab\u6210\u6548\u986f\u8457\uff0c\u7d93\u6fdf\u5c55\u73fe\u97cc\u6027\uff0c\u4f46\u5f8c\u671f\u5065\u5eb7\u6307\u6a19\u4e0b\u6ed1\u4e14\u8ca7\u5bcc\u5dee\u8ddd\u64f4\u5927\u3001\u5bb6\u5ead\u66b4\u529b\u8207\u751f\u80b2\u7387\u4e0b\u964d\u7b49\u793e\u6703\u554f\u984c\u6d6e\u73fe\u3002\u9019\u4e9b\u767c\u73fe\u70ba\u672a\u4f86\u75ab\u60c5\u7ba1\u7406\u7b56\u7565\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u7d93\u9a57\u8207\u555f\u793a\u3002<\/td>Asian Pacific Journal of Health Economics and Policy.<\/td><\/td><\/tr>
2024\u5e7411\u670824\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Automatic localization and deep convolutional generative adversarial network-based classification of focal liver lesions in computed tomography images: A preliminary study<\/a><\/td>\u672c\u7814\u7a76\u958b\u767c\u4e86\u4e00\u500b\u57fa\u65bc\u6df1\u5ea6\u5b78\u7fd2\u7684\u809d\u81df\u75c5\u8b8a\u5b9a\u4f4d\u8207\u5206\u985e\uff08DLLC\uff09\u7cfb\u7d71\uff0c\u65e8\u5728\u5354\u52a9\u91ab\u5e2b\u89e3\u8b80CT\u5f71\u50cf\u4e2d\u7684\u809d\u81df\u5c40\u90e8\u75c5\u8b8a\u3002\u7cfb\u7d71\u5728\u5b9a\u4f4d\u7684\u5e73\u5747\u7cbe\u5ea6\u90540.81\uff0c\u5206\u985e\u6e96\u78ba\u7387\u90540.97\uff0c\u4e14\u5c0d\u65bc\u76f4\u5f91\u5c0f\u65bc3 cm\u7684\u75c5\u8b8a\u6e96\u78ba\u7387\u70ba0.83\uff0c\u5c0d\u65bc\u5927\u65bc3 cm\u7684\u75c5\u8b8a\u70ba0.87\u3002\u8a72\u7cfb\u7d71\u63d0\u4f9b\u4e86\u4e00\u7a2e\u6e96\u78ba\u4e14\u975e\u4fb5\u5165\u6027\u7684\u8a3a\u65b7\u65b9\u6cd5\uff0c\u5c0d\u809d\u75c5\u5b78\u5bb6\u548c\u653e\u5c04\u79d1\u91ab\u5e2b\u5177\u6709\u91cd\u8981\u50f9\u503c\u3002<\/td>Journal of Gastroenterology and Hepatology<\/td>3.7<\/td><\/tr>
2024\u5e74 10\u670822\u65e5<\/td>\u6881\u7acb\u9716\u526f\u6559\u6388\u7b49\u4eba<\/td>The Role of Digital Health Under Taiwan’s National Health Insurance System: Progress and Challenges<\/a><\/td>\u6578\u4f4d\u5065\u5eb7\u6db5\u84cb\u4e86\u6578\u4f4d\u6280\u8853\u5728\u91ab\u7642\u9818\u57df\u7684\u61c9\u7528\uff0c\u5c0d\u6539\u5584\u91ab\u7642\u670d\u52d9\u7684\u53ef\u53ca\u6027\u3001\u8cea\u91cf\u548c\u7cfb\u7d71\u6548\u7387\u5177\u6709\u91cd\u8981\u610f\u7fa9\u3002\u672c\u7814\u7a76\u63a2\u8a0e\u53f0\u7063\u570b\u6c11\u5065\u5eb7\u4fdd\u96aa\u4e0b\u7684\u6578\u4f4d\u5065\u5eb7\uff0c\u7279\u5225\u662f\u5728COVID-19\u5927\u6d41\u884c\u671f\u9593\u7684\u5f71\u97ff\uff0c\u4e26\u805a\u7126\u5927\u6578\u64da\u7ba1\u7406\u8207\u5206\u6790\uff08\u5982MediCloud\u3001My Health Bank\/NHI Mobile Easy Access\uff09\u53ca\u5275\u65b0\u670d\u52d9\u6a21\u5f0f\uff08\u5982\u9060\u8ddd\u91ab\u7642\uff09\u3002\u7814\u7a76\u6307\u51fa\uff0c\u6536\u5165\u8f03\u9ad8\u53ca\u60a3\u6709\u6162\u6027\u75c5\u6216\u91cd\u75c7\u8005\u8f03\u591a\u4f7f\u7528\u9060\u8ddd\u91ab\u7642\uff0c\u4e26\u5f37\u8abf\u6578\u4f4d\u4fe1\u4efb\u8207\u6578\u4f4d\u9d3b\u6e9d\u7684\u6311\u6230\u3002<\/td>Health systems and reform<\/td><\/td><\/tr>
2024\u5e747 \u670830\u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Short-chain fatty acids ameliorate imiquimod-induced skin thickening and IL-17 levels and alter gut microbiota in mice: a metagenomic association analysis<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u77ed\u93c8\u8102\u80aa\u9178\uff08SCFAs\uff09\u5c0d\u60a3\u6709\u985e\u9280\u5c51\u75c5\u7684\u8001\u9f20\u76ae\u819a\u8868\u578b\u3001\u5168\u8eab\u6027\u708e\u75c7\u53ca\u8178\u9053\u83cc\u7fa4\u7684\u5f71\u97ff\u3002\u4f7f\u7528\u54aa\u5511\uff08IMQ\uff09\u8655\u7406\u7684\u5c0f\u9f20\u4f5c\u70ba\u6a21\u578b\uff0c\u4e26\u9032\u884c\u57fa\u56e0\u7d44\u5b78\u7814\u7a76\uff0c\u5206\u6790SCFAs\u6216\u6297IL-17\u6297\u9ad4\u5c0d\u76ae\u819a\u539a\u5ea6\u3001\u708e\u75c7\u6307\u6a19\u548c\u7cde\u4fbf\u5fae\u751f\u7269\u7684\u5f71\u97ff\u3002\u7d50\u679c\u986f\u793a\uff0cSCFAs\u6539\u5584\u4e86IMQ\u8a98\u5c0e\u7684\u76ae\u819a\u589e\u539a\u3001\u813e\u81df\u589e\u91cd\u53ca\u8840\u6e05IL-17F\u6c34\u5e73\uff0c\u6548\u679c\u8207\u6297IL-17\u6cbb\u7642\u76f8\u4f3c\u3002SCFAs\u9084\u63d0\u9ad8\u4e86\u5fae\u751f\u7269\u591a\u6a23\u6027\uff0c\u4e26\u6539\u8b8a\u4e86\u8178\u9053\u83cc\u7fa4\u7d44\u6210\uff0c\u9810\u793a\u8457\u5176\u8207\u7cd6\u985e\u964d\u89e3\u53ca\u82ef\u4e19\u6c28\u9178\u4ee3\u8b1d\u7b49\u904e\u7a0b\u6709\u95dc\u3002<\/td>Scientific reports<\/td><\/td><\/tr>
2024\u5e74 7 \u6708 27 \u65e5<\/td>\u5433\u8c9e\u5b9c\u4e3b\u4efb\u7b49\u4eba<\/td>Association between Air Quality Index and the risk of rosacea: a nationwide population-based cohort study<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u7a7a\u6c23\u54c1\u8cea\u6307\u6578\uff08AQI\uff09\u8207\u73ab\u7470\u75e4\u7621\u767c\u75c5\u7387\u7684\u95dc\u806f\u3002\u7814\u7a76\u5206\u6790\u4e86\u4f86\u81ea\u53f0\u7063\u570b\u6c11\u5065\u5eb7\u4fdd\u96aa\u8cc7\u6599\u5eab\u768421,709,479\u540d\u53c3\u8207\u8005\uff0c\u767c\u73fe\u6bcf\u55ae\u4f4dAQI\u589e\u52a0\uff0c\u73ab\u7470\u75e4\u7621\u98a8\u96aa\u589e\u52a05%\u3002\u6839\u64daAQI\u503c\u5c07\u53c3\u8207\u8005\u5206\u70ba\u56db\u7d44\uff0c\u7d50\u679c\u986f\u793a\u8f03\u9ad8AQI\u7d44\u5225\u7684\u73ab\u7470\u75e4\u7621\u98a8\u96aa\u986f\u8457\u589e\u52a0\uff08Q2\u70ba1.82\u500d\u3001Q3\u70ba4.48\u500d\u3001Q4\u70ba7.22\u500d\uff09\u3002\u6b64\u5916\uff0cPM2.5\u3001\u4e8c\u6c27\u5316\u786b\uff08SO2\uff09\u548c\u4e00\u6c27\u5316\u78b3\u7684\u66b4\u9732\u8207\u73ab\u7470\u75e4\u7621\u98a8\u96aa\u589e\u52a0\u6709\u95dc\uff0cPM10\u5247\u8207\u8f03\u4f4e\u98a8\u96aa\u76f8\u95dc\u3002\u7814\u7a76\u986f\u793aAQI\u8207\u73ab\u7470\u75e4\u7621\u767c\u75c5\u7387\u4e4b\u9593\u5b58\u5728\u986f\u8457\u7684\u5291\u91cf\u53cd\u61c9\u95dc\u4fc2\u3002<\/td>Clinical And Experimental Dermatology<\/td>3.7<\/td><\/tr>
2024\u5e74 7 \u6708 23 \u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Clinical guidelines for early hepatocellular carcinoma treatment options: a systematic review and bibliometric analysis<\/a><\/td>\u672c\u7814\u7a76\u7cfb\u7d71\u6027\u56de\u98672017\u81f32024\u5e74\u4e3b\u8981\u809d\u81df\u5b78\u6703\u768423\u9805\u6307\u5357\uff0c\u5206\u6790\u809d\u7d30\u80de\u764c\u65e9\u671f\u6cbb\u7642\u4e2d\u5c04\u983b\u6d88\u878d\uff08RFA\uff09\u8207\u624b\u8853\u5207\u9664\u7684\u63a8\u85a6\u8b8a\u5316\u3002\u7d50\u679c\u986f\u793a\uff0cRFA\u5728\u67d0\u4e9b\u60a3\u8005\u7fa4\u9ad4\u4e2d\u7684\u61c9\u7528\u652f\u6301\u5ea6\u63d0\u5347\uff0c\u800c\u624b\u8853\u5207\u9664\u4ecd\u56e0\u5176\u7a69\u56fa\u8b49\u64da\u57fa\u790e\u7372\u5f97\u5f37\u70c8\u63a8\u85a6\u30022023\u5e74\u65e5\u672c\u6307\u5357\u7372\u5f97\u6700\u9ad8\u8cea\u91cf\u8a55\u5206\uff0c\u4f46\u6307\u5357\u5236\u5b9a\u4e2d\u7684\u5229\u5bb3\u95dc\u4fc2\u4eba\u53c3\u8207\u5ea6\u666e\u904d\u8f03\u4f4e\u3002\u672c\u7814\u7a76\u5f37\u8abf\u6307\u5357\u9700\u6301\u7e8c\u66f4\u65b0\uff0c\u4e26\u547c\u7c72\u9032\u884c\u9ad8\u8cea\u91cf\u7684\u76f4\u63a5\u6bd4\u8f03\u7814\u7a76\uff0c\u4ee5\u9032\u4e00\u6b65\u512a\u5316\u65e9\u671f\u809d\u7d30\u80de\u764c\u7684\u6cbb\u7642\u7b56\u7565\u3002<\/td>International journal of surgery<\/td>12.5<\/td><\/tr>
2024\u5e74 7 \u6708 17 \u65e5<\/td>\u5433\u4fca\u7a4e\u6559\u6388\u8207\u6797\u9a30\u7acb\u540c\u5b78\u7b49\u4eba<\/td>Reduced atopic march risk in pediatric atopic dermatitis patients prescribed dupilumab versus conventional immunomodulatory therapy: A population-based cohort study<\/a><\/td>\u672c\u7814\u7a76\u6bd4\u8f03\u809d\u5207\u9664\u8853\uff08LR\uff09\u8207\u5c04\u983b\u6d88\u878d\u8853\uff08RFA\uff09\u5728\u65e9\u671f\u809d\u7d30\u80de\u764c\uff08ES-HCC\uff09\u6cbb\u7642\u4e2d\u7684\u6548\u679c\uff0c\u9032\u884c\u4e86\u57fa\u65bc\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\u7684Meta\u5206\u6790\u3002\u901a\u904e\u6aa2\u7d22\u591a\u500b\u6578\u64da\u5eab\uff0c\u5171\u7d0d\u51659\u9805RCT\uff0c\u6d89\u53ca1516\u540d\u60a3\u8005\u3002\u7d50\u679c\u986f\u793a\uff0cLR\u57282\u5e74\u82075\u5e74\u7684\u7e3d\u751f\u5b58\u7387\uff08OS\uff09\u4e0a\u8207RFA\u7121\u986f\u8457\u5dee\u7570\uff0c\u4f46\u5728\u7121\u75c5\u751f\u5b58\u7387\uff08DFS\uff09\u65b9\u9762\uff0cLR\u5448\u73fe\u4e00\u5b9a\u512a\u52e2\uff082\u5e74DFS HR=1.40\uff1b5\u5e74DFS HR=1.37\uff09\uff0c\u4f46\u7d71\u8a08\u6548\u529b\u6709\u9650\u3002\u6574\u9ad4\u7570\u8cea\u6027\u4f4e\uff0c\u7d50\u679c\u53ef\u9760\u3002\u7814\u7a76\u5efa\u8b70\u9700\u9032\u4e00\u6b65\u5927\u578bRCT\u4ee5\u660e\u78baLR\u8207RFA\u7684\u7642\u6548\u5dee\u7570\u3002<\/td>Journal of the American Academy of Dermatology<\/td>12.8<\/td><\/tr>
2024\u5e74 6 \u6708 14 \u65e5<\/td>\u8607\u5efa\u7dad\u4e3b\u4efb\u7b49\u4eba<\/td>The association between proton-pump inhibitor use and recurrence of hepatocellular carcinoma after hepatectomy<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0eDupilumab\u5c0d\u5152\u7ae5\u6fd5\u75b9\uff08AD\uff09\u60a3\u8005\u5728\u9632\u6b62\u904e\u654f\u9032\u5c55\uff08\u5373\u904e\u654f\u6027\u54ee\u5598\u6216\u904e\u654f\u6027\u9f3b\u708e\uff09\u4e2d\u7684\u6548\u679c\uff0c\u4e26\u8207\u50b3\u7d71\u514d\u75ab\u8abf\u7bc0\u5291\u9032\u884c\u6bd4\u8f03\u3002\u901a\u904e\u56de\u9867\u6027\u968a\u5217\u7814\u7a76\uff0c\u5206\u67902192\u540d\u60a3\u8005\u7684\u6578\u64da\uff0c\u7d50\u679c\u986f\u793a\uff0cDupilumab\u7d44\u76843\u5e74\u7d2f\u7a4d\u9032\u5c55\u7387\u986f\u8457\u4f4e\u65bc\u50b3\u7d71\u6cbb\u7642\u7d44\uff0820.09%\u5c0d27.22%\uff1bP < .001\uff09\u3002Dupilumab\u7d44\u5728\u6574\u9ad4\u904e\u654f\u9032\u5c55\u3001\u54ee\u5598\u53ca\u904e\u654f\u6027\u9f3b\u708e\u7684\u98a8\u96aa\u6e1b\u5c11\u5747\u986f\u8457\uff08\u98a8\u96aa\u6bd4\u5206\u5225\u70ba0.68\u30010.60\u548c0.69\uff09\u3002\u5e74\u8f15\u60a3\u8005\u7684\u98a8\u96aa\u6e1b\u5c11\u6548\u679c\u66f4\u986f\u8457\u3002<\/td>Journal of gastroenterology and hepatology<\/td> 3.7<\/td><\/tr>
2024\u5e74 6 \u6708 12 \u65e5<\/td>\u6881\u7acb\u9716\u526f\u6559\u6388\u7b49\u4eba<\/td>Physical Fitness and Risk of Mental Disorders in Children and Adolescents<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u9577\u671f\u4f7f\u7528\u8cea\u5b50\u6cf5\u6291\u5236\u5291\uff08PPI\uff09\u8207\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u7d93\u624b\u8853\u6cbb\u7642\u5f8c\u5fa9\u767c\u7684\u95dc\u806f\u3002\u7d0d\u51656037\u540d\u63a5\u53d7\u809d\u5207\u9664\u8853\u7684HCC\u60a3\u8005\uff0c\u6839\u64daPPI\u4f7f\u7528\u5291\u91cf\u5206\u70ba\u56db\u7d44\u3002\u7d50\u679c\u986f\u793a\uff0cPPI\u4f7f\u7528\u8005\u7684\u4e2d\u4f4d\u7121\u5fa9\u767c\u751f\u5b58\u671f\uff08RFS\uff09\u986f\u8457\u8f03\u975e\u4f7f\u7528\u8005\u9577\uff08\u8abf\u6574\u5f8c\u98a8\u96aa\u6bd40.57\uff0cP < 0.001\uff09\u3002\u5176\u4e2d\uff0c\u9577\u671f\u4f7f\u7528PPI\uff08\u2265180 cDDD\uff09\u7684\u60a3\u8005\u5fa9\u767c\u98a8\u96aa\u986f\u8457\u8f03\u4f4e\uff08adj-HR: 0.50\uff0cP < 0.001\uff09\u3002\u7136\u800c\uff0cPPI\u4f7f\u7528\u5c0d\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u7121\u986f\u8457\u5f71\u97ff\u3002\u7d50\u8ad6\u70ba\uff0c\u9577\u671f\u4f7f\u7528PPI\u53ef\u80fd\u8207HCC\u624b\u8853\u5f8c\u8f03\u597d\u7684RFS\u76f8\u95dc\u3002<\/td>JAMA Pediatrics<\/td> 24.7<\/td><\/tr>
2024\u5e74 6 \u6708 1 \u65e5<\/td>\u674e\u9a30\u88d5\u526f\u6559\u6388\u7b49\u4eba<\/td>Validating the Baveno Elastography Criteria of Advanced Liver Fibrosis in Two-Dimensional Shear Wave Elastography: A Prospective Pathology-Based Study<\/a><\/td>\u672c\u7814\u7a76\u5206\u6790\u53f0\u7063\u7d04200\u842c\u540d10\u81f311\u6b72\u5152\u7ae5\u548c\u9752\u5c11\u5e74\u7684\u8cc7\u6599\uff0c\u63a2\u8a0e\u8eab\u9ad4\u7d20\u8cea\u8207\u5fc3\u7406\u75be\u75c5\u98a8\u96aa\u4e4b\u95dc\u806f\u3002\u7d50\u679c\u986f\u793a\uff0c\u5fc3\u80ba\u9069\u80fd\uff08CF\uff09\u3001\u808c\u8010\u529b\uff08ME\uff09\u8207\u808c\u529b\uff08MP\uff09\u8868\u73fe\u8f03\u4f73\u8005\uff0c\u5176\u7126\u616e\u3001\u6182\u9b31\u53ca\u6ce8\u610f\u529b\u4e0d\u8db3\u904e\u52d5\u75c7\uff08ADHD\uff09\u98a8\u96aa\u8f03\u4f4e\uff0c\u4e14\u5177\u5291\u91cf\u53cd\u61c9\u95dc\u4fc2\u3002\u6027\u5225\u5206\u6790\u767c\u73fe\uff0c\u6539\u5584CF\u3001ME\u548cMP\u5747\u80fd\u964d\u4f4e\u5fc3\u7406\u75be\u75c5\u98a8\u96aa\uff0c\u6548\u679c\u56e0\u6027\u5225\u7565\u6709\u5dee\u7570\u3002\u7814\u7a76\u5f37\u8abf\u63d0\u5347\u8eab\u9ad4\u7d20\u8cea\u53ef\u80fd\u5177\u6709\u9810\u9632\u5fc3\u7406\u75be\u75c5\u7684\u6f5b\u529b\uff0c\u5efa\u8b70\u9032\u4e00\u6b65\u63a2\u7d22\u9ad4\u9069\u80fd\u8a08\u756b\u7684\u6548\u76ca\u3002<\/td>Digestive diseases<\/td>2<\/td><\/tr>
2024\u5e74 5 \u6708 2 \u65e5<\/td>\u694a\u61f7\u58f9\u526f\u7814\u7a76\u54e1\u7b49\u4eba<\/td>Polygenic Risk Score Predicts Earlier-Onset Adult Systemic Lupus Erythematosus and First-Year Renal Diseases in a Taiwanese Cohort<\/a><\/td>\u672c\u7814\u7a76\u65e8\u5728\u9a57\u8b49Baveno\u6a19\u6e96\u5728\u4e8c\u7dad\u526a\u5207\u6ce2\u5f48\u6027\u6210\u50cf\uff082D-SWE\uff09\u4e2d\u7684\u61c9\u7528\u3002\u5171\u7d0d\u5165101\u540d\u9032\u884c\u809d\u6d3b\u6aa2\u7684\u60a3\u8005\uff0c\u4e26\u4f7f\u7528\u77ac\u6642\u5f48\u6027\u6210\u50cf\uff08TE\uff09\u82072D-SWE\u9032\u884c\u809d\u786c\u5ea6\u6e2c\u91cf\u3002\u7d50\u679c\u986f\u793a\uff0cTE\u82072D-SWE\u7684AUROC\u503c\u5206\u5225\u70ba0.92\u548c0.93\uff08p=0.61\uff09\uff0c\u9748\u654f\u5ea6\u905494.44%\uff0c\u7279\u7570\u6027\u70ba86.00%\u548c88.00%\u3002\u4f7f\u7528Baveno\u6a19\u6e96\uff0cTE\u548c2D-SWE\u7684AUROC\u503c\u5206\u5225\u70ba0.91\u548c0.93\uff08p=0.36\uff09\uff0c\u9748\u654f\u5ea6\u548c\u7279\u7570\u6027\u5747\u8f03\u9ad8\u3002\u6b64\u7814\u7a76\u8b49\u5be6\u4e862D-SWE\u5728\u81e8\u5e8a\u4e2d\u53ef\u4f5c\u70ba\u6709\u6548\u7684Baveno\u6a19\u6e96\u66ff\u4ee3\u5de5\u5177\u3002<\/td>RMD open<\/td>5.1<\/td><\/tr>
2024\u5e74 4 \u6708 18 \u65e5<\/td>\u8607\u5efa\u7dad\u4e3b\u4efb\u7b49\u4eba<\/td>Conventional and machine learning-based risk scores for patients with early-stage hepatocellular carcinoma<\/a><\/td>\u672c\u7814\u7a76\u65e8\u5728\u5229\u7528\u591a\u57fa\u56e0\u98a8\u96aa\u5206\u6578\uff08PRS\uff09\u9810\u6e2c\u53f0\u7063\u6210\u4eba\u7cfb\u7d71\u6027\u7d05\u6591\u72fc\u7621\uff08SLE\uff09\u60a3\u8005\u7684\u814e\u81df\u9810\u5f8c\u3002\u7814\u7a76\u7d0d\u51652782\u540dSLE\u60a3\u8005\u53ca11128\u540d\u5c0d\u7167\u7d44\uff0c\u4f7f\u7528\u57fa\u56e0\u7d44\u55ae\u6838\u82f7\u9178\u591a\u614b\u6027\uff08SNP\uff09\u9663\u5217\u9032\u884c\u57fa\u56e0\u5206\u578b\u3002C+T\u6cd5\u5efa\u69cb\u7684SLE-PRS\u6a21\u578b\uff0c\u50c5\u5305\u542b27\u500bSNP\uff0c\u9810\u6e2c\u814e\u81df\u640d\u5bb3\u7684AUC\u90540.629\uff0c\u512a\u65bc\u5176\u4ed6\u6a21\u578b\u3002\u5728\u6700\u9ad8\u56db\u5206\u4f4d\u6578\u7684\u60a3\u8005\u4e2d\uff0c\u767c\u75c5\u5e74\u9f61\u8f03\u65e9\uff0c\u4e14\u9996\u6b21\u8a3a\u65b7\u5f8c\u4e00\u5e74\u5167\u814e\u81df\u53d7\u7d2f\u98a8\u96aa\u8f03\u9ad8\u3002\u7d50\u8ad6\u70ba\uff0cSLE-PRS\u8207\u65e9\u671f\u767c\u75c5\u3001\u814e\u81df\u53d7\u7d2f\u53ca\u8840\u6e05\u5b78\u6aa2\u6e2c\u6709\u95dc\uff0c\u5c0dSLE\u60a3\u8005\u814e\u81df\u75be\u75c5\u7684\u7be9\u67e5\u8207\u6cbb\u7642\u5177\u6709\u6f5b\u5728\u50f9\u503c\u3002<\/td>Clinical and molecular hepatology<\/td> 14<\/td><\/tr>
2024\u5e74 4 \u6708 11 \u65e5<\/td>\u8607\u5efa\u7dad\u4e3b\u4efb\u7b49\u4eba<\/td>Prognostic Nutritional Index as a Prognostic Factor for Very Early-Stage Hepatocellular Carcinoma<\/a><\/td>\u672c\u7814\u7a76\u65e8\u5728\u6bd4\u8f03\u50b3\u7d71\u65b9\u6cd5\u8207\u6a5f\u5668\u5b78\u7fd2\uff08ML\uff09\u5728\u9810\u6e2c\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u65e9\u671f\u60a3\u8005\u9810\u5f8c\u4e2d\u7684\u8868\u73fe\u3002\u7d0d\u51651,411\u540dBCLC 0\u81f3A\u671f\u6cbb\u7642\u672a\u66fe\u63a5\u53d7\u6cbb\u7642\u7684HCC\u60a3\u8005\uff0c\u5206\u70ba\u8a13\u7df4\u7d44\uff08n=988\uff09\u548c\u9a57\u8b49\u7d44\uff08n=423\uff09\u3002\u7814\u7a76\u958b\u767c\u4e86\u5169\u500b\u98a8\u96aa\u8a55\u5206\uff08CATS-IF\u548cCATS-INF\uff09\uff0c\u5206\u5225\u4f7f\u7528Cox\u56de\u6b78\u6a21\u578b\u548cLASSO Cox\u56de\u6b78\u65b9\u6cd5\u9810\u6e2c\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u3002\u7d50\u679c\u986f\u793a\uff0cCATS-IF\u548cCATS-INF\u5747\u512a\u65bc\u5176\u4ed6\u9810\u5f8c\u8a55\u5206\uff0c\u4e14CATS-INF\u8868\u73fe\u7565\u512a\uff0c\u5177\u6709\u8f03\u4f4e\u7684Akaike\u4fe1\u606f\u6e96\u5247\u503c\u3002<\/td>Clinical and translational gastroenterology<\/td>3.2<\/td><\/tr>
2024\u5e74 4 \u6708 1 \u65e5<\/td>\u694a\u61f7\u58f9\u526f\u7814\u7a76\u54e1\u7b49\u4eba<\/td>Persistently high HBsAg levels during HBeAg-seropositive stage predict lower risk of hepatocellular carcinoma in chronic hepatitis B patients<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u975e\u4fb5\u5165\u6027\u8840\u6e05\u6a19\u8a18\u6307\u6578\u5c0d\u6975\u65e9\u671f\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u9810\u5f8c\u7684\u9810\u6e2c\u80fd\u529b\u3002\u5171\u7d0d\u5165446\u540d\u60a3\u8005\uff0c\u5206\u6790\u4e86\u9810\u6e2c\u7e3d\u751f\u5b58\u7387\uff08OS\uff09\u7684\u8840\u6e05\u6a19\u8a18\u7269\u53ca\u9810\u5f8c\u5206\u6578\u3002\u7d50\u679c\u986f\u793a\uff0c\u9810\u5f8c\u71df\u990a\u6307\u6578\uff08PNI\uff09\u5728\u9810\u6e2cOS\u65b9\u9762\u8868\u73fe\u6700\u4f73\uff0c\u5177\u6709\u6700\u4f4e\u7684\u8d64\u6c60\u4fe1\u606f\u6e96\u5247\uff08AIC 846.407\uff09\u3002\u5c07\u60a3\u8005\u5206\u70ba\u9ad8\u98a8\u96aa\uff08PNI <45\uff09\u548c\u4f4e\u98a8\u96aa\uff08PNI \u226545\uff09\u7d44\uff0c\u4e94\u5e74OS\u5206\u5225\u70ba60.8%\u548c83.4%\uff08P < 0.001\uff09\u3002PNI\u662f\u6975\u65e9\u671fHCC\u60a3\u8005\u9810\u6e2cOS\u7684\u6700\u4f73\u6307\u6a19\u3002<\/td>Alimentary pharmacology & therapeutics<\/td>6.6<\/td><\/tr>
2024\u5e74 2 \u6708 27 \u65e5<\/td>\u5433\u8c9e\u5b9c\u4e3b\u4efb\u7b49\u4eba<\/td>Association of air quality index (AQI) with incidence of atopic dermatitis in Taiwan: A nationwide population-based cohort study<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u6162\u6027\u4e59\u578b\u809d\u708e\uff08CHB\uff09HBeAg\u967d\u6027\u60a3\u8005\u4e2d\uff0cHBsAg\u6c34\u5e73\u5728\u9810\u6e2c\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u767c\u5c55\u4e2d\u7684\u4f5c\u7528\u3002\u5f9eREVEAL-HBV\u968a\u5217\u4e2d\u7d0d\u5165319\u540dHBeAg\u967d\u6027\u60a3\u8005\uff0c\u4e26\u6839\u64daHBsAg\u8ecc\u8de1\u5c07\u5176\u5206\u70ba\u6301\u7e8c\u9ad8HBsAg\u7d44\uff08A\u7d44\uff09\u548c\u975e\u7a69\u5b9a\u7d44\uff08B\u7d44\uff09\u3002\u7d50\u679c\u986f\u793a\uff0cA\u7d44HCC\u5e74\u767c\u75c5\u7387\u70ba0.37%\uff0cB\u7d44\u70ba1.16%\uff08p = 0.03\uff09\u3002\u591a\u8b8a\u91cf\u5206\u6790\u767c\u73fe\uff0c\u5e74\u9f61\uff1e40\u6b72\u3001\u57fa\u56e0\u578bC\u53ca\u975e\u7a69\u5b9a\u7d44\u70baHCC\u7368\u7acb\u9810\u6e2c\u56e0\u5b50\u3002\u7d50\u8ad6\u70ba\u6301\u7e8c\u9ad8HBsAg\u6c34\u5e73\u7684\u60a3\u8005HCC\u98a8\u96aa\u8f03\u4f4e\u3002<\/td>Journal of the American Academy of Dermatology<\/td>12.8<\/td><\/tr>
2024\u5e74 2 \u6708 2 \u65e5<\/td>\u5433\u8c9e\u5b9c\u4e3b\u4efb\u7b49\u4eba<\/td>Association between vitiligo and risk of retinal detachment: a population-based cohort study in Taiwan<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u7a7a\u6c23\u54c1\u8cea\u6307\u6578\uff08AQI\uff09\u8207\u7570\u4f4d\u6027\u76ae\u819a\u708e\uff08AD\uff09\u767c\u751f\u7387\u7684\u95dc\u806f\u3002\u5206\u6790\u4f86\u81ea\u53f0\u7063\u5168\u6c11\u5065\u5eb7\u4fdd\u96aa\u7814\u7a76\u8cc7\u6599\u5eab\u768421,278,938\u540d\u53c3\u8207\u8005\uff0c\u4e26\u8a08\u7b97\u5176\u9577\u671f\u5e73\u5747AQI\u503c\u30022008\u81f32018\u5e74\u9593\u5171\u767c\u73fe199,205\u4f8bAD\u65b0\u767c\u75c5\u4f8b\u3002\u7d50\u679c\u986f\u793a\uff0c\u96a8\u8457AQI\u503c\u589e\u52a0\uff0cAD\u98a8\u96aa\u986f\u8457\u4e0a\u5347\uff0c\u5176\u4e2dAQI\u6700\u9ad8\u7684Q4\u7d44\u98a8\u96aa\u6700\u9ad8\uff08\u8abf\u6574\u5371\u96aa\u6bd4\uff1a13.20\uff09\u3002\u6bcf\u589e\u52a01\u55ae\u4f4dAQI\uff0cAD\u98a8\u96aa\u589e\u52a07%\u3002\u7814\u7a76\u7d50\u679c\u8b49\u5be6AQI\u8207AD\u767c\u751f\u7387\u5448\u986f\u8457\u5291\u91cf\u53cd\u61c9\u95dc\u4fc2\u3002<\/td>Clinical and experimental dermatology<\/td>3.7<\/td><\/tr>
2024\u5e74 1 \u6708 25 \u65e5<\/td>\u5433\u8c9e\u5b9c\u4e3b\u4efb\u7b49\u4eba<\/td>Risk of Type 1 Diabetes Mellitus in Patients with Atopic Dermatitis: A Nationwide Population-Based Cohort Study<\/a><\/td>\u672c\u7814\u7a76\u63a2\u8a0e\u767d\u6591\u60a3\u8005\u8996\u7db2\u819c\u812b\u843d\uff08RD\uff09\u7684\u98a8\u96aa\uff0c\u4f7f\u75282007\u81f32018\u5e74\u53f0\u7063\u570b\u6c11\u5065\u5eb7\u4fdd\u96aa\u8cc7\u6599\u5eab\u9032\u884c\u5168\u570b\u6027\u968a\u5217\u7814\u7a76\u300221,132\u540d\u767d\u6591\u60a3\u8005\u8207\u672a\u60a3\u767d\u6591\u8005\u6309\u5e74\u9f61\u3001\u6027\u5225\u53ca\u5408\u4f75\u75c7\u5339\u914d\u3002\u7d50\u679c\u986f\u793a\uff0c\u767d\u6591\u60a3\u8005RD\u767c\u751f\u7387\u986f\u8457\u8f03\u9ad8\uff08\u6821\u6b63\u5f8c\u98a8\u96aa\u6bd4[aHR] 1.44\uff09\uff0c\u63a5\u53d7\u5149\u7642\u3001\u5168\u8eab\u985e\u56fa\u9187\u6216\u514d\u75ab\u6291\u5236\u6cbb\u7642\u7684\u60a3\u8005\u98a8\u96aa\u66f4\u9ad8\uff08aHR 1.57\uff09\u3002\u6b64\u98a8\u96aa\u572810\u5e74\u96a8\u8a2a\u671f\u9593\u4fdd\u6301\u8f03\u9ad8\u3002<\/td>Dermatology<\/td>12.8 <\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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\u7814\u8a0e\u6703\u91cd\u8981\u7814\u7a76\u767c\u8868<\/strong><\/p>\n\n\n\n

\u7814\u8a0e\u6703\u540d\u7a31<\/td>\u4f5c\u8005<\/td>\u8ad6\u6587\u540d\u7a31<\/td>\u6458\u8981\u6216\u767c\u8868\u6d77\u5831<\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Longitudinal fib-4 changes associated with risk of hepatocellular carcinoma in patients with metabolic dysfunction fatty liver disease: a nationwide 8-year cohort study<\/td><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u5433\u4fca\u7a4e\u6559\u6388\u7b49\u4eba<\/td>Association between air pollution and risk of inflammatory bowel diseases: a nationwide cohort study<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u5f8c\u7814\u7a76\u54e1Mohapatra Sulagna\u7b49\u4eba<\/td>Enhancing non-invasive focal liver lesion diagnosis: explainable artificial intelligence-driven radiomics analysis with non-contrast mri<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u5f8c\u7814\u7a76\u54e1Gupta Pushpanjali \u7b49\u4eba<\/td>Transparent ai-driven methodology for demonstrating the adequacy of non-contrast computed tomography in the diagnosis of focal liver lesions through the integration of radiomics, clinical insights: a comprehensive three-dimensional study<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u73ed\u5f90\u9298\u5b8f\u540c\u5b78\u7b49\u4eba<\/td>Effect modification between ADH1B, ALDH2, ALDH3A1 genetic polymorphisms
and the common risk behaviors for esophageal squamous cell carcinoma<\/td>		\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u73ed\u90ed\u6b63\u6d69\u540c\u5b78\u7b49\u4eba<\/td>Metabolic maladaptation of the intestinal host-microbiota interface drives alcohol-induced injury.<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u73ed\u90ed\u6b63\u6d69\u540c\u5b78\u7b49\u4eba<\/td>Increased risk of antimicrobial resistance in cirrhosis patients with rifaximin use.<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u535a\u58eb\u73ed\u9673\u5f65\u4f36\u540c\u5b78\u7b49\u4eba<\/td>Association between longitudinal fibrosis marker changes and hepatocellular carcinoma recurrence after definitivetherapy.<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr>
2025 Digestive Disease Week<\/strong>
San Diego<\/strong><\/td>		\u78a9\u58eb\u73ed\u859b\u7af9\u73fa\u540c\u5b78\u7b49\u4eba
<\/td>		FIB-4 associated with risk of hepatocellular carcinoma in patients with alcohol-related liver diseases<\/td>\u9ede\u6211\u9023\u7d50<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

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